Update, Blog Post Nicole Johnson Update, Blog Post Nicole Johnson

FOXG1 Research Foundation ASGCT Recap -> On Track to a FOXG1 Gene Therapy

The FOXG1 Research Foundation is thrilled to share a recap of our participation at the 2024 American Society of Gene and Cell Therapy (ASGCT) conference in Baltimore. This conference marked a significant milestone for our foundation, truly a "coming out party" to Pharma for our commitment to developing a gene therapy for FOXG1 syndrome.

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Blog Post Nicole Johnson Blog Post Nicole Johnson

2022 Impact Report

2022 Research Highlights (see details below)

  • Breakthrough gene therapy results showing rescue of FOXG1 brain structure, behavior, memory and cognition symptoms in animal models

  • Positive results on initial compound drug screens to identify molecules to increase FOXG1 levels; now moving forward to larger screens

  • Never-before understanding of FOXG1 biology uncovered from six FOXG1 patient human cell lines and mouse models 

  • Successful testing of guide RNAs to increase FOXG1 expression with a CRISPRa Cas-9 system

  • Discovered ASO sequences (antisense gene therapy) to modulate FOXG1 expression; testing initiated with Creyon Bio  

  • FOXG1 data package presented to several biotech companies with high interest


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News, Blog Post Nicole Johnson News, Blog Post Nicole Johnson

Help FOXG1 Ukrainian Family Rebuild!

The FOXG1 Research Community has helped get a FOXG1 family safely out of the warn-torn Ukraine! Now, they have to rebuild thier lives. Eva is a 3-ear-old child with the severe rare disease called FOXG1 syndrome. She suffers from seizures and is disabled. They are on thier way to safely, but they lost everything. This is how you can help. Thank you!

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Blog Post Nicole Johnson Blog Post Nicole Johnson

2021 Impact Report

The FOXG1 Research Foundation is dedicated to driving science towards therapeutics and ultimately a cure for every person in the world affected with FOXG1 syndrome. While accelerating research, we are also focused on advocating for and supporting families along this difficult journey. We cannot do this without you. In 2021 we raised nearly $3M. Thank you for your support!



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